Globus Pallidus Internus Deep Brain Stimulation Using Frame-Based vs. Frameless Stereotaxy in Dystonia: A Single-Center Experience

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Globus pallidus deep brain stimulation in dystonia.

Globus pallidus deep brain stimulation (GPi-DBS) is a useful alternative in the treatment of dystonia. Patients selected for GPi-DBS were prospectively rated with the Unified Dystonia Rating Scale (UDRS). Also, "blinded" videotape assessments were performed. Eleven patients were identified. Compared with pre-DBS scores, there were improvements in mean total UDRS score (15.3%) and in the followi...

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Deep brain stimulation electrode used for radiofrequency lesion of the globus pallidus internus in dystonia.

BACKGROUND There have recently been increasing case reports in the literature of deep brain stimulation (DBS) electrodes used for lesioning with satisfactory clinical success in the treatment of Parkinson disease and tremor. METHODS After preliminary experiments of radiofrequency (RF) lesioning with a quadripolar DBS lead, a paediatric case of generalized primary dystonia was treated by RF le...

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Deep brain stimulation of globus pallidus internus for DYT1 positive primary generalized dystonia

BACKGROUND Deep brain stimulation (DBS) of the globus pallidus internus (GPi) is recommended as a promising technique for the management of the primary generalized dystonia (PGD) with DYT1 gene mutation. We present the first report of DBS results in Iranian patients with DYT1 positive PGD. METHODS Nine patients who suffered from severely disabling DYT1 positive PGD consecutively were recruite...

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Differential response of dystonia and parkinsonism following globus pallidus internus deep brain stimulation in X-linked dystonia-parkinsonism (Lubag).

BACKGROUND X-linked dystonia-parkinsonism (XDP; DYT3; Lubag) is an adult-onset hereditary progressive dystonia/parkinsonism which is typically minimally responsive to pharmacological treatment. CASE REPORT We report a 63- year-old man with a diagnosis of XDP who underwent bilateral globus pallidus internus deep brain stimulator (GPi-DBS) placement. His course initially began with right hand t...

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Weight change after globus pallidus internus or subthalamic nucleus deep brain stimulation in Parkinson's disease and dystonia.

BACKGROUND Weight gain has been described in Parkinson's disease (PD) patients after subthalamic nucleus (STN) deep brain stimulation (DBS). OBJECTIVES We examined change in weight following DBS in both PD and dystonia patients to further investigate the role of disease and brain target (STN or globus pallidus internus, GPi) specificity. METHODS Data was retrospectively collected on 61 PD D...

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ژورنال

عنوان ژورنال: Frontiers in Neurology

سال: 2021

ISSN: 1664-2295

DOI: 10.3389/fneur.2021.643757